The adhesion molecules of inflammation

Vascular endothelial adhesion molecules and tissue inflammation.

Pentoxifylline Decreases Serum Level of Adhesion Molecules in Atherosclerosis Patients

Background: Inflammation is involved in development, progression, and complications of atherosclerotic disease. Clinical studies have indicated that the level of monocyte chemoattractant protein 1 (MCP-1), IL-18, and adhesion molecules correlates with the severity of atherosclerosis and can predict future cardiovascular events. Experimental studies have shown pentoxifylline (PTX) reduces these ...

Cellular Adhesion and Adhesion Molecules

In recent years, cell adhesion and cell adhesion molecules have been shown to be important for many normal biological processes, including embryonic cell migration, immune system functions and wound healing. It has also been shown that they contribute to the pathogenesis of a large number of common human disorders, such as rheumatoid arthritis and tumor cell metastasis in cancer. In this review...

Adhesion Molecules at the Synapse

Communication between neurons is mediated mainly by chemical synapses, at which neurotransmitters are released by the presynaptic neuron, diffuse across the narrow cleft, and activate receptors located on postsynaptic neurons. Synapses provide the structural and functional basis for the formation and maintenance of the complex neural networks that exist in the brain. This process is governed by...

Adhesion molecules in implantation.

At implantation, trophectoderm attaches to the apical uterine luminal epithelial cell surface. Molecular anatomy studies in humans and mice, and data from experimental models have identified several adhesion molecules that could take part in this process: integrins of the alpha v family, trophinin, CD44, cad-11, the H type I and Lewis y oligosaccharides and heparan sulfate. The endometrial cell...